What Is the “Microalbumin” Urine Test and Why Is It Important in Diabetes?
Patient's Query
My father has diabetes for many years. Recently, I noticed his urine looks frothy.
When we went to the doctor, he asked for a microalbumin urine test.
I got scared. Does this mean his kidneys are damaged? If this test comes positive, is it serious? Can it be controlled or reversed?
Endocrinologist Answers
This is a very common and very important question, and you are right to ask.
Let me explain this in very simple words.

First, what do kidneys normally do?
Think of the kidney like a very fine water filter:
- It cleans the blood.
- It removes waste into urine.
- It does NOT allow protein to leak into urine.
Protein should stay inside the body.
What happens in diabetes?
In diabetes, high sugar slowly damages very tiny blood vessels in many organs. This is called microvascular damage (small vessel damage). The kidney has millions of tiny filters.
When sugar stays high for years:
- These tiny filters become weak.
- Small amounts of protein start leaking into urine.
- This happens much before creatinine becomes abnormal.
This early protein leak is called microalbuminuria.
Why does urine look frothy?
Protein in urine makes bubbles and foam.
So:
- Frothy urine can be an early warning sign.
- It does NOT always mean severe kidney failure.
- But it means the filter is under stress.
What exactly is the microalbumin urine test checking?
The test looks for very small amounts of protein in urine that:
- Cannot be picked up by routine urine tests. Requires a specific urine protein test.
- Appear early, before permanent damage happens.
Most doctors now use a test called UACR (Urine Albumin-to-Creatinine Ratio).
This adjusts for urine concentration and is more accurate.
Should you panic if the test is positive?
No. Please don’t panic.
A positive microalbumin test means:
- Early kidney stress.
- Not kidney failure.
- Not dialysis stage.
This stage is often controllable and progression can be slowed or stopped.
Why is this test so important?
Because:
- Creatinine rises late.
- Microalbumin rises early.
- Early detection is equals to better protection.
If missed:
- Protein leak increases.
- Kidney damage progresses.
- Creatinine rises later.
- Then damage becomes harder to reverse.
What helps if microalbumin is detected early?
- Good sugar control.
- Good blood pressure control.
- Certain BP medicines protect kidneys.
- Avoid smoking.
- Regular follow-up.
With proper care:
- Protein leak can reduce.
- Kidney function can stay stable for many years.
How often should this test be done?
For people with diabetes:
- At least once every year.
- More often if already positive.
This is as important as eye check and foot check.
Simple takeaway for patients
- Frothy urine can be an early warning sign
- Micro-albumin test looks for early kidney stress, not kidney failure
- Early detection saves kidneys
- Good diabetes control protects kidneys
This test helps doctors act early, not to scare you.
References:
- https://diabetesjournals.org/care/article/47/Supplement_1/S244/153944/13-Older-Adults-Standards-of-Care-in-Diabetes-2024
- https://www.kidney.org/kidney-topics/albuminuria-proteinuria
- https://kdigo.org/guidelines/diabetes-ckd/
- https://www.uptodate.com/contents/diabetic-kidney-disease-beyond-the-basics
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7061225/
Disclaimer: The information provided in this Q&A is for educational purposes only and should not be considered as medical advice. Always consult with a qualified healthcare professional for personalized medical guidance and treatment recommendations.